Brigham and Women’s Hospital and Harvard Medical School Division of Women’s Health and Department of Psychiatry Postdoctoral Fellow – Neuroimaging and Obesity/Depression

Brigham and Women’s Hospital and Harvard Medical School

Division of Women’s Health and Department of Psychiatry

Postdoctoral Fellow – Neuroimaging and Obesity/Depression

Position: We are inviting applications for a postdoctoral fellowship position in clinical neuroscience and neuroimaging related to reward processing in obesity and depression (PI: Laura Holsen). The focus of our lab is on understanding factors (including genotype, sex, neuroendocrine functioning, neural circuitry activity, diet, stress, and mood) that drive appetite, eating behaviors, and weight change, with a broad goal of ameliorating negative health outcomes and chronic diseases associated with obesity and disordered eating, such as diabetes, cardiovascular disease, and psychiatric disorders such as depression. In our work, we explore these themes using various neuroimaging approaches (BOLD fMRI, arterial spin labeling) in combination with neuroendocrine measurements and behavioral assessments, with foundational work focused on genetic mechanisms. We work in close collaboration with colleagues in psychiatry, nutrition, endocrinology, and radiology/functional neuroimaging.

In addition to hands-on conduct of experiments and neuroimaging acquisition, duties will include analysis of fMRI, serology, and behavioral data, manuscript preparation, presentation of findings at conferences, and management of research assistants. The Fellow will participate actively in ongoing studies of appetite hormones and brain activity, contribute to grant submissions, complete pilot projects, have opportunities for publications and presentations using new and existing datasets, and be encouraged to prepare independent research grants. Mentorship will be provided by the PI, along with opportunities to interact with a diverse team of collaborators including clinicians with expertise in obesity treatment, neuroscientists, neuroanatomists, psychiatrists, and physicists. 

Brigham and Women’s Hospital/Harvard Medical School offers an excellent environment to engage in multidisciplinary, dynamic research training through various collaborative opportunities. Resources include state of the art imaging facilities with several 3T scanners at the Brigham and Women’s MRI Research Center (BWMRC) and clinical research coordination through the Physiologic Unit of the BWH Center for Clinical investigation [part of the Harvard Clinical and Translational Science Center (CTSC), now called the Harvard Catalyst].

Qualifications/Requirements: A Ph.D. is required in the area of affective, nutritional, or cognitive neuroscience, psychology, or a related discipline. Qualified applicants must have experience in working with clinical populations (individuals with disordered eating; psychiatric disorders), a solid foundation in conducting fMRI studies (including collection, analysis, and interpretation of fMRI data), and a track record of first-author research papers published in peer-reviewed journals. Highly desirable qualifications include experience in the implementation of the Trier Social Stress Test, familiarity with SPM, Matlab, and UNIX/Linux environments, and programming skills. Applicants must possess excellent verbal and written communication skills and the ability to work both within a team and independently. We are looking for highly motivated, self-driven, creative, and interactive scientists.

How to apply: Interested candidates should email their CV, a statement of research and long-term career goals, and contact information for 3 references to lholsen@partners.org.